TLS Online TPP Program

#Question id: 4664


Which one of the following statements about E.coli RNA poymerase is false?

#Unit 3. Fundamental Processes
  1. The holoenzyme includes the sigma factor

  2. The core enzymes includes the sigma factor

  3. It requires Mg2+ for its activity

  4. It requires Zn2+ for it activity

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TLS Online TPP Program

#Question id: 4582

#Unit 11. Evolution and Behavior

 Fossils found in strata reveal that ________.

TLS Online TPP Program

#Question id: 4081

#Unit 3. Fundamental Processes

Which of the following regulatory scenarios of cell-type-specific expression of fibronectin isoforms in humans is (are) consistent with information on known splicing factors?

a. A Tra-like splicing factor expressed in fibroblasts is required for inclusion of EIIIA and EIIIB exons.

b. An Sxl-like splicing factor is required in hepatocytes for exclusion of EIIIA and EIIIB exons.

c. A Tra-2-like factor enhances binding of the cleavage/polyadenylation complex in fibroblasts.

d. A Dsx-like protein is required to inhibit transcription of the fibronectin gene.

TLS Online TPP Program

#Question id: 1386

#Unit 4. Cell Communication and Cell Signaling

The ability of a population of fibroblasts to migrate along the surface of a tissue culture dish depends on adhesion between the cell surface and the extracellular matrix molecules coating the dish. The dish is coated with laminin, and the only cell-surface protein capable of binding laminin is a cell-adhesion protein called an integrin. Integrins are integral plasma-membrane proteins that function as heterodimers. Under these conditions the rate at which a fibroblast can migrate along the laminin coated culture dish is proportional to the strength of adhesion between the cell and the laminin substrate. The table below lists the rate of cell migration observed for fibroblasts genetically engineered to generate the indicated phenotypes. One explanation for the effect of overexpression of the cytoplasmic domain of the integrin beta subunit is that this domain normally functions to bind a cytoplasmic factor necessary for integrin function. Which of the following would be the most informative experiment to identify the cytoplasmic factor?

TLS Online TPP Program

#Question id: 3771

#Unit 3. Fundamental Processes

In DNA replication, the resulting daughter molecules contain one strand of the original parental DNA and one new strand. What is the explanation for this phenomenon

TLS Online TPP Program

#Question id: 23160

#Unit 13. Methods in Biology

Texas is a fluorescent dye which emits a colour?