TLS Online TPP Program

#Question id: 4787


In humans, PKU (phenylketonuria) is a recessive disease caused by enzyme inefficiency at step A in the following simplified reaction sequence, and AKU (alkaptonuria) is a recessive disease due to enzyme inefficiency in one of the steps summarized as step B here:A person with PKU and homozygous for normal of other character was married a person with AKU and homozygous for normal of other character. What is expected phenotypes in their children?

#Unit 8. Inheritance Biology
  1. All normal                  

  2. All having PKU only    

  3. All having AKU              

  4.  All having both PKU and AKU

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TLS Online TPP Program

#Question id: 15659

#Unit 8. Inheritance Biology

You calculate map distances between genes A, B, and C based on all pairwise dihybrid crosses. When you perform the trihybrid cross to verify your results, you discover that, despite analysis of a very large number of progeny, you have only about half as many double crossover progeny as you expect. Which explanation is the most reasonable?

TLS Online TPP Program

#Question id: 17267

#Unit 8. Inheritance Biology

In humans, albinism (unpigmented skin, hair, and eyes) is due to an enzymatic deficiency, and it is an autosomal recessive trait. Suppose that in a small country of one million people (“Generation 1”), there are 500 aa albinos and 9000 Aa heterozygous carriers. Estimate q, the frequency of allele a, in Generation 1. Show your calculations. 

TLS Online TPP Program

#Question id: 17268

#Unit 8. Inheritance Biology

In humans, albinism (unpigmented skin, hair, and eyes) is due to an enzymatic deficiency, and it is an autosomal recessive trait. Suppose that in a small country of one million people (“Generation 1”), there are 500 aa albinos and 9000 Aa heterozygous carriers. Estimate p, the frequency of allele A, in Generation 1?

TLS Online TPP Program

#Question id: 17269

#Unit 8. Inheritance Biology

In humans, albinism (unpigmented skin, hair, and eyes) is due to an enzymatic deficiency, and it is an autosomal recessive trait. Suppose that in a small country of one million people (“Generation 1”), there are 500 aa albinos and 9000 Aa heterozygous carriers. In the next generation of 1 million individuals (Generation 2), what are the expected numbers of aa albinos and Aa carriers? (Assume random mating and all other HardyWeinberg conditions.)

TLS Online TPP Program

#Question id: 17807

#Unit 8. Inheritance Biology

In humans, albinism (unpigmented skin, hair, and eyes) is due to an enzymatic deficiency, and it is an autosomal recessive trait. Suppose that in a small country of one million people (“Generation 1”), there are 500 aa albinos and 9000 Aa heterozygous carriers. What is the probability that a child will be albino if: Both parents are non-albino members of Generation 2?

TLS Online TPP Program

#Question id: 17808

#Unit 8. Inheritance Biology

In humans, albinism (unpigmented skin, hair, and eyes) is due to an enzymatic deficiency, and it is an autosomal recessive trait. Suppose that in a small country of one million people (“Generation 1”), there are 500 aa albinos and 9000 Aa heterozygous carriers. What is the probability that a child will be albino if: One parent is a non-albino member of Generation 2, and the other parent is a non-albino member of Generation 1.