Which of the following processes is an early step in the whole-genome shotgun approach to sequencing?

#Question id: 4170

#Unit 3. Fundamental Processes

 Shifting of the reading frame by one nucleotide results in __.

#Question id: 11332

#Unit 10. Ecological Principles

The most plausible hypothesis to explain why species richness is higher in tropical than in temperate regions is that

 A) tropical communities are older.

 B) tropical regions generally have more available water and higher levels of solar radiation.

 C) higher temperatures cause more rapid speciation.

 D) diversity increases as evapotranspiration decreases.

#Question id: 1518

#Unit 4. Cell Communication and Cell Signaling

Following statements are regarding to the some cancers harbor characteristic chromosome alterations. Chronic myelogenous leukemia (CML), a common leukemia in humans, was found to be associated with the Philadelphia chromosome.

A. Philadelphia chromosome is generated by a translocation between chromosomes 22 and 9. The two chromosomes exchange their terminal regions, which leads to a characteristic alteration in the size of chromosome 9.

B. At the breakpoint of this translocation, a new fusion protein, the BCR-ABL fusion, is generated.

C. The BCR-ABL fusion protein is a constitutively active kinase that phosphorylates multiple signal-transducing proteins.

D. If this translocation occurs in a hematopoietic cell in the bone marrow, the activity of the chimeric BCR-ABL oncogene dephosphorylate proteins thereby activating many intracellular signal-transducing proteins.

Which of the following statements are incorrect?

#Question id: 34123

#Unit 7. System Physiology – Animal

#Question id: 4394

#Unit 3. Fundamental Processes

A new insulin gene was isolated and a study was planned to look at the function of the promoter region. Which of the following would be the best choice for this study?

A. southern analysis

B. immunoblotting

C. reporter gene assay

D. PCR