#Question id: 26584
#Unit 3. Fundamental Processes
#Question id: 1521
#Unit 4. Cell Communication and Cell Signaling
we examine how the deregulation of growth-promoting and growth-inhibiting signaling pathways contributes to tumorigenesis. Mutations-
A. A mutation that alters a single amino acid (valine to glutamine) in the transmembrane region of the HER2 receptor
B. A deletion that causes loss of the extracellular ligand-binding domain in the EGF receptor Results-
i. dimerization of the receptor, even in the absence of the normal EGF-related ligand, transforming it into the oncoprotein, a constitutively active kinase
ii. to constitutive activation of the kinase activity of the resulting oncoprotein
iii. no dimerization, even in the presence of the normal EGF-related ligand, repression of kinase activity
which of the following results are displayed after these mutations?
#Question id: 1069
#Unit 4. Cell Communication and Cell Signaling
Diseases of short duration frequently followed by long-term immunity are referred to as
#Question id: 1404
#Unit 4. Cell Communication and Cell Signaling
Which of the following are transcription factors?
#Question id: 4790
#Unit 8. Inheritance Biology
The F2 genotypes of two independently assorting gene A and B with complete dominance result in a 9 : 3 : 3 : 1 ratio of phenotypes if there is no interaction between the genes. Following modify phenotypic ratio of 9:3:3:1 given as following table (p - phenotype) Which of the following correct matching of gene interaction and their deviated phenotype ratio?