TLS Online TPP Program

#Question id: 7097


What property of the mammalian embryo permits the production of chimeric mice?

#Unit 5. Developmental Biology
  1. The inner cell mass is highly regulative, so that extra cells derived from the inner cell mass of a different embryo are incorporated without causing defects.
  2. f half of the cells of the inner cell mass are removed and replaced with cells from half of a different embryo's inner cell mass, the embryo will heal and develop normally.
  3. The embryo can develop outside the womb, making surgical manipulations possible
  4. Blastomeres separated at the two-cell stage will regulate and each forms a normal embryo.
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TLS Online TPP Program

#Question id: 19723

#Unit 3. Fundamental Processes

Reduction in the telomerase activity after the cell cycle is the notion of 
a) Cell ageing
b) Senescence 
c) Apoptosis

TLS Online TPP Program

#Question id: 19733

#Unit 3. Fundamental Processes

Extensive shortening of telomeres eventually leads to 

TLS Online TPP Program

#Question id: 19734

#Unit 3. Fundamental Processes

Some of the statements are given regarding shelterin choose the correct 
a) Shelterin is the complex of telomeric protein
b) Shelterin functions to protect telomeres from DNA damage repair pathways
c) In mammals, six telomeric proteins (TRF1, TRF2, Rap1, TIN2, TPP1, and POT1) comprises a complex.
d) Shelterin also regulate telomere length control by telomerase

TLS Online TPP Program

#Question id: 19735

#Unit 3. Fundamental Processes

In mammals, six telomeric proteins (TRF1, TRF2, Rap1, TIN2, TPP1, and POT1) comprises a complex which of the following is incorrect regrarding these telomeric protein
a) TRF1, TRF2, Rap1, binds to double stranded of DNA
b) TIN2 does not binds to DNA at all
c) POT1 binds to the GT tail extended by telomerase
d) TIN2 interacts with the two duplex telomeric DNA-binding proteins TRF1 and TRF2 as well as with TPP1

TLS Online TPP Program

#Question id: 19736

#Unit 3. Fundamental Processes

Which of the following shelterin protein interacts with the two duplex telomeric DNA-binding proteins TRF1 and TRF2 as well as with TPP1

TLS Online TPP Program

#Question id: 19737

#Unit 3. Fundamental Processes

Choose the incorrect statement regarding telomerase