TLS Online TPP Program

#Question id: 32407


Deuterated acetyl-coenzyme A (-CD3 instead of –CH3) was used in an experiment to study the TCA cycle. Upon analysis of the metabolites, it was found that deuterium (D) was present in a wide variety of compounds; even compounds not associated with the citric acid cycle. This is due to

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. Frequent methylation of proteins & enzymes
  2. Frequent acetylation of proteins & enzymes
  3. Frequent carboxymethylation of proteins & enzymes
  4. Frequent carboxylation of enzymes
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TLS Online TPP Program

#Question id: 28688

#Unit 2. Cellular Organization

Ca2+ is released into the cytosol from the ER lumen through the operation of____

TLS Online TPP Program

#Question id: 28689

#Unit 2. Cellular Organization

 A special type of endoplasmic reticulum of muscle cells that involved in increasing the cytosolic Ca2+ concentration for skeletal muscle contraction ? 

TLS Online TPP Program

#Question id: 28690

#Unit 2. Cellular Organization

A pathway of protein trafficking that flows through the ER is called____

TLS Online TPP Program

#Question id: 28691

#Unit 2. Cellular Organization

ER targeting sequence___

TLS Online TPP Program

#Question id: 28692

#Unit 2. Cellular Organization

Which one of the following statements about signal recognition particles (SRPs) is correct?
a) It is a cytosolic ribonucleoprotein
b) It docks with a receptor on the surface of the ER membrane.
c) It is an integral membrane protein
d) It transiently binds to both the ER signal sequence at the C-terminus and the large (60S) ribosomal subunit
e) It acts as a scaffold for the hexamer

TLS Online TPP Program

#Question id: 28693

#Unit 2. Cellular Organization

There are some given statements about co-translational translocation in endoplasmic reticulum

a)SRP and the nascent polypeptide chain–ribosome complex bind to the integral membrane translocon

b)SRP and the nascent polypeptide chain–ribosome complex is strengthened by the binding of GTP to both the SRP and its receptor.

c)ER signal sequence emerges from the ribosome, it is bound by a signal recognition particle (SRP)

d)Hydrolysis of the bound GTP accompanies disassembly of the SRP and SRP receptor

e)Hydrolysis of the bound GTP initiates opening of the translocon, where translocation can take place


Which of the following statement is incorrect?