Practice Questions

TLS Online TPP Program

#Question id: 7130

Hematopoietic stem cells can be isolated and grown in culture; if one wished to control their differentiation into either neutrophils or macrophages, what colony stimulating factors could be used?

#Unit 5. Developmental Biology

First, GM-CSF and IL-3 would be added to trigger formation of the granulocyte/macrophage lineage; then, the addition of either G-CSF or M-CSF would select between further differentiation as neutrophils or macrophages, respectively.
Since stem-cell factor (SCF) would maintain the cells as stem cells, the elimination of SCF would trigger differentiation into granulocyte/macrophage precursors; no further manipulation would be necessary.
The stem cells could be simultaneously stimulated with G-CSF, M-CSF, GM-CSF, and IL-3; half would become neutrophils and the other half would become macrophages; no further control is possible.
Since hematopoietic stem cells can become only erythrocytes, neutrophils, or macrophages, and no other cell types, the elimination of erythropoietin (EPO) would be sufficient to trigger formation of neutrophils and macrophages.

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TLS Online TPP Program

#Question id: 27940

#Unit 9. Diversity of Life Forms

Sibling species are those species which is___

TLS Online TPP Program

#Question id: 27941

#Unit 1. Molecules and their Interaction Relevant to Biology

Some of the following statement are made regarding the Enzymes of glycolysis along with their Coenzyme (s) or Cofactor (s) and Inhibitor (s)

a. Phosphoglucoisomerase having Mg2+ as Cofactor and can be inhibited by 2-deoxyglucose 6-phosphate

b. Aldolase having Zn2+ as Cofactor, can be inhibited by Chelating agents

c. Enolase having Mg, Mn22+ Cd2 as Cofactor, can be inhibited by Fluoride + phosphate

d. Phosphofructokinase having NAD as Coenzyme can be inhibited by Iodoacetate

Which of the following is correct

TLS Online TPP Program

#Question id: 27942

#Unit 1. Molecules and their Interaction Relevant to Biology

Glycolytic enzymes along with them their class is mentioned

(1) Phosphoglucoisomerase, Phosphotriose isomerase, Phosphoglycerate mutase belongs to Isomerases

(2) Hexokinase, Phosphofructokinase, Phosphoglycerate kinase, Pyruvate kinase belongs to Transferases

(3) Aldolase, Enolase belongs to Lysases

(4) Glyceraldehyde 3-phosphate dehydrogenase belongs to Oxidoreductases

Which of the following is correct

TLS Online TPP Program

#Question id: 27943

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following reaction is catalyzes by enolase during Glycolysis

TLS Online TPP Program

#Question id: 27944

#Unit 1. Molecules and their Interaction Relevant to Biology

Which one of the following is not the component of Co-A

TLS Online TPP Program

#Question id: 27945

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following statements is true regarding the payoff phase of glycolysis

a. Each molecule of glyceraldehyde 3-phosphate is oxidized and phosphorylated by ATP to form 1,3-bisphosphoglycerate

b. Each molecule of glyceraldehyde 3-phosphate is oxidized and phosphorylated by inorganic phosphate to form 1,3-bisphosphoglycerate

c. Oxidative phosphorylation of 3-Phosphoglycerate produces one NADH

d. Oxidative phosphorylation of glyceraldehyde 3-phosphate, produces one NADH