TLS Online TPP Program

#Question id: 7158


If the nerve supply to a newt limb is severed before amputation, how will this affect regeneration?

#Unit 5. Developmental Biology
  1. It will have no effect, since regeneration involves growth of new muscle, bone, and connective tissue.
  2. Regeneration of most tissues will occur normally, but regeneration of the nerves will not occur.
  3. Outgrowth will occur, but the identity of the limb will be lost and normal proximo-distal patterning will not occur.
  4. A blastema will form but will not grow, and regeneration will fail.
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TLS Online TPP Program

#Question id: 857

#Unit 1. Structure and Function of Biomolecules

The aggregation of nonpolar side chains in the interior of a protein is favored by

TLS Online TPP Program

#Question id: 858

#Unit 1. Structure and Function of Biomolecules

Unfolded protein response (UPR)

TLS Online TPP Program

#Question id: 859

#Unit 1. Structure and Function of Biomolecules

Which one statement is incorrect about ATG genes;

TLS Online TPP Program

#Question id: 860

#Unit 1. Structure and Function of Biomolecules

Select true ‘T’ AND false ‘F’ about ubiquitinylation

I. These ubiquitin-like modifiers control processes as diverse as nuclear import,

II. Regulated by the ubiquitin-like modifier Sumo, and autophagy,

III. Regulated by the ubiquitin-like modifier Atg8.

IV. For a protein to be efficiently degraded, it must be linked to a chain of at least four tandemly linked ubiquitin molecules in which Lys 34 of each ubiquitin forms an isopeptide bond with the C-terminal carboxyl group of the following ubiquitin.

TLS Online TPP Program

#Question id: 861

#Unit 1. Structure and Function of Biomolecules

Alexander Varshavsky discovered, the half-lives of many cytoplasmic proteins vary with the identities of their N-terminal residues via the so-called N-end rule:-

A. Destabilizing N-terminal residues Asp, Arg, Leu, Lys, and Phe have half-lives of

i. Only 2 to 3 minutes,

B. Stabilizing N-terminal residues Ala, Gly, Met, Ser, Thr, and Val have half-lives of

ii. >10 hours in prokaryotes

iii. >20 hours in eukaryotes.

TLS Online TPP Program

#Question id: 862

#Unit 1. Structure and Function of Biomolecules

Match the following

lysosomal protein degradation pathwaysFound in
1. Nonselectivea-well-nourished cells

i-containing the pentapeptide

Lys-Phe-Glu-Arg-Gln

2- Selectiveb-starving cells