Following statements are related to the Epigenetic regulation of Hox gene expression in the chick limb .

A. Hoxa13 is normally not expressed during early limb bud outgrowth.

B. Hoxa13 is normally expressed during early limb bud outgrowth.

C. Inhibition of histone deacetylases with a TSA-coated bead implanted into the early limb bud results in precocious Hoxa13 expression and specifically reduced skeletal elements of the zeugopod

D. Inhibition of HAT proteins with a TSA-coated bead implanted into the early limb bud results in Hoxa13 expression and specifically reduced skeletal elements of the zeugopod

E. The epigenetic hold on gene Hoxa13 expression to allow the necessary time for zeugopod development.

F. The epigenetic hold on gene Hoxa13 expression to allow the necessary time for autopod development.

Which of the following combinations are correct?

TLS Online TPP Program

#Question id: 32714

#Unit 1. Molecules and their Interaction Relevant to Biology

The existence of an enzyme-substrate complex can be experimentally demonstrated by

a. X-ray crystallography

b. ESR

c. NMR

d. Fluorimetery

TLS Online TPP Program

#Question id: 32715

#Unit 1. Molecules and their Interaction Relevant to Biology

Which model correctly represents the graph

 

TLS Online TPP Program

#Question id: 32716

#Unit 1. Molecules and their Interaction Relevant to Biology

The given relationship is known as

TLS Online TPP Program

#Question id: 32717

#Unit 1. Molecules and their Interaction Relevant to Biology

The enzyme urease enhances the rate of urea hydrolysis at pH 8.0 and 20oC by a factor of 1014. If a given quantity of urease can completely hydrolyze a given quantity of urea in 5.0 min at 20oC and pH 8.0, how long would it take for this amount of urea to be hydrolyzed under the same conditions in the absence of urease?

TLS Online TPP Program

#Question id: 32718

#Unit 1. Molecules and their Interaction Relevant to Biology

When enzyme solutions are heated, there is a progressive loss of catalytic activity over time due to denaturation of the enzyme. A solution of the enzyme hexokinase incubated at 45oC lost 50% of its activity in 12 min, but when incubated at 45oC in the presence of a very large concentration of one of its substrates, it lost only 3% of its activity in 12 min. What is correct explanation

TLS Online TPP Program

#Question id: 32919

#Unit 2. Cellular Organization

Which control system triggers the early mitotic events that lead to chromosome alignment on the mitotic spindle in metaphase?