TLS Online TPP Program

#Question id: 7212


The regeneration blastema forms from pluripotent stem cells called clonogenic neoblast. If cNeoblasts are essential for regeneration, their total loss should prevent regeneration. Following statements are made in respect to planaria regeneration are given below.

(A) The gene sigma/zeta is expressed by all neoblasts and has become the most common marker for their identification across planarian species.

(B)   In planaria, Wnt/β-catenin functions to establish dorsal ventral polarity of the regenerating flatworm.

(C)   Inhibition of Wnt/β-catenin signaling in regeneration-deficient species yields fully functional regenerated heads.

(D)   If β-catenin is eliminated from the posterior (tail-forming) blastema by RNA interference, that blastema will form a tail.

Which of the above statements are true?

#Unit 5. Developmental Biology
  1. A and D     
  2. A and C
  3. C and D            
  4. B and D