#Question id: 7230

Following statements are being made regarding gradients of specific translational inhibitors in drosophila.

A. In the anterior region, Bicoid protein prevents translation of the caudal message by binds to a specific region of caudal’s 3′UTR. Here, bicoid recruits Bin3 (a translation inhibitor) which prevents translation of caudal in the anterior of the embryo.

B. In the posterior region, Nanos protein prevents translation of the hunchback message by forming a complex with several other ubiquitous proteins, including Pumilio and Brat. This complex binds to the 3’UTR of the hunchback message, where it recruits d4EHP and prevents the hunchback message from attaching to ribosomes.

C. In the anterior region, Bicoid protein prevents translation of the caudal message by binds to a specific region of caudal’s 5′UTR. Here, bicoid recruits pumilio and brat (a translation inhibitor) which prevents translation of caudal in the anterior of the embryo.

D. In the posterior region, Nanos protein prevents translation of the hunchback message by forming a complex with several other ubiquitous proteins, including bin3 and smaug. This complex binds to the 3’UTR of the hunchback message, where it recruits d4EHP and prevents the hunchback message from attaching to ribosomes.

Which of the following combination are incorrect?