#Question id: 447
#Unit 1. Structure and Function of Biomolecules
In glycolysis, fructose 1,6-bisphosphate is converted to two products with a standard free-energy change (DG'°) of 23.8 kJ/mol. Under what conditions encountered in a normal cell will the free-energy change (DG) be negative, enabling the reaction to proceed spontaneously to the right?
#Question id: 448
#Unit 1. Structure and Function of Biomolecules
During glycolysis, glucose 1-phosphate is converted to fructose 6-phosphate in two successive reactions: Glucose 1-phosphate -> glucose 6-phosphate DG'° = –7.1 kJ/mol Glucose 6-phosphate -> fructose 6-phosphate DG'° = +1.7 kJ/mol DG'° for the overall reaction is:
#Question id: 449
#Unit 1. Structure and Function of Biomolecules
The standard free-energy changes for the reactions below are given. Phosphocreatine -> creatine + Pi DG'° = –43.0 kJ/mol ATP -> ADP + Pi DG'° = –30.5 kJ/mol What is the overall DG'° for the following reaction? Phosphocreatine + ADP -> creatine + ATP
#Question id: 450
#Unit 1. Structure and Function of Biomolecules
The DG'° values for the two reactions shown below are given.
Oxaloacetate + acetyl-CoA + H2O -> citrate + CoASH DG'° = –32.2 kJ/mol
Oxaloacetate + acetate -> citrate DG'° = –1.9 kJ/mol
What is the DG'° for the hydrolysis of acetyl-CoA?
Acetyl-CoA + H2O -> acetate + CoASH + H+
#Question id: 451
#Unit 1. Structure and Function of Biomolecules
The standard reduction potentials (E'°) for the following half reactions are given.
Fumarate + 2H+ + 2e– -> succinate E'° = +0.031 V
FAD + 2H+ + 2e– -> FADH2 E'° = –0.219 V
If you mixed succinate, fumarate, FAD, and FADH2 together, all at l M concentrations and in the presence of succinate dehydrogenase, which of the following would happen initially?
#Question id: 452
#Unit 1. Structure and Function of Biomolecules
E'° of the NAD+/NADH half reaction is –0.32 V. The E'° of the oxaloacetate/malate half reaction is –0.175 V. When the concentrations of NAD+, NADH, oxaloacetate, and malate are all 10–5 M, the “spontaneous” reaction is: