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TLS Online TPP Program

#Question id: 11544

When a steroid hormone and a polypeptide hormone exert similar effects on a population of target cells, then ________.

#Unit 7. System Physiology – Animal
  1. the steroid and polypeptide hormones must use the same biochemical mechanisms
  2. the steroid and polypeptide hormones must bind to the same receptor protein
  3. the steroid hormones affect the synthesis of effector proteins, whereas polypeptide hormones activate effector proteins already present in the cell

  4. the steroid hormones affect the activity of certain proteins within the cell, whereas polypeptide hormones directly affect the processing of mRNA

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TLS Online TPP Program

#Question id: 15619

#Unit 13. Methods in Biology

Wild type E. coli metabolizes the sugar lactose by expressing the enzyme ß-galactosidase. You have isolated a mutant that you call lac1–, which cannot synthesize ß-galactosidase and cannot grow on lactose (Lac–). During an condition isolate a mutation that constitutively expresses abnormally high levels of ßgalactosidase, which you designate lacc. Preliminary P1 transduction experiments indicate that lacc  is linked to the Tn5 insertion.  To map lacc  relative to lac1– you set up two reciprocal crosses. In the first cross you grow P1 on a strain that carries the Tn5 insertion and the lac1– mutation. You then use this lysate to infect a lacc mutant and select for Kanr. From 100 Kanr transductants examined, 20 are Lac–, 76 express ß-galactosidase constitutively and 4 show normal ß-galactosidase expression. In the second cross you grow P1 on a strain that carries the Tn5 insertion and the lacc mutation. You then use this lysate to infect a lac1– mutant, and select for Kanr. From 100 Kanr transductants examined, 81 are Lac– and 19  express ß-galactosidase constitutively. So what will be the correct order of  the Tn5 insertion and the lac1– and lacc  mutations. Express any measured distances as cotransduction frequencies.
TLS Online TPP Program

#Question id: 109

#Unit 1. Molecules and their Interaction Relevant to Biology

A deficiency in the synthesis of sphingomyelins or cerebrosides will most likely result in the improper formation of
TLS Online TPP Program

#Question id: 5670

#Unit 5. Developmental Biology

Embryonic stem cells can be induced in the laboratory to differentiate into muscle, nerve, pancreatic, and other specialized cell types. It has recently become possible to trigger the dedifferentiation of somatic cells back into pluripotent cells (so-called induced pluripotent stem cells or iPS cells) by artificially enhancing the production of a relatively small number of key transcriptional factors known to be required for maintenance of pluripotency. Examples of such transcription factors are OCT4 and NANOG. The production of OCT4 and NANOG (and other key regulatory proteins) is stimulated by a transcription factor known as FOXP1, a member of the Forkhead family of DNA-binding proteins. There are two isoforms of FOXP1.

Which of the following statement regarding to FOXP1 is incorrect?
TLS Online TPP Program

#Question id: 21001

#Unit 12. Applied Biology

Bioremediation of inorganic contaminants is primarily based on suitable 
TLS Online TPP Program

#Question id: 6541

#General Aptitude

What is the next number in the sequence ?

2, 3, 4, 7, 6, 11, 8, 15, 10, .......