TLS Online TPP Program

#Question id: 892


Assisted protein folding is mediated by a group of proteins known as chaperons, which of the following statements is incorrectly reperesents chaperon activity;

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. chaperon help to fold, unfolded and partially folded polypeptide chains to disrupt the improper association of exposed hydrophobic segments

  2. All molecular chaperones operate by binding to an unfolded or aggregated protein’s, and molecular chaperon donot requires ATP for their activity

  3. molecular chaperones function to lift folding polypeptides out of the false minima in their folding funnels

  4. molecular chaperones were first described as heat shock proteins (Hsp) because their rate of synthesis is increased at elevated temperatures

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TLS Online TPP Program

#Question id: 991

#Unit 1. Molecules and their Interaction Relevant to Biology

The conversion of UTP to CTP involves ________.

TLS Online TPP Program

#Question id: 992

#Unit 1. Molecules and their Interaction Relevant to Biology

Fatty acids are activated to acyl-CoAs and the acyl group is further transferred to carnitine because:

TLS Online TPP Program

#Question id: 993

#Unit 1. Molecules and their Interaction Relevant to Biology

What is the correct order of function of the following enzymes of beta oxidation?

1. B-Hydroxyacyl-CoA dehydrogenase

2. Thiolase

3. Enoyl-CoA hydratase

4. Acyl-CoA dehydrogenase

TLS Online TPP Program

#Question id: 994

#Unit 1. Molecules and their Interaction Relevant to Biology

If the 16-carbon saturated fatty acid palmitate is oxidized completely to carbon dioxide and water (via the B-oxidation pathway and the citric acid cycle), and all of the energy-conserving products are used to drive ATP synthesis in the mitochondrion, the net yield of ATP per molecule of palmitate is:

TLS Online TPP Program

#Question id: 995

#Unit 1. Molecules and their Interaction Relevant to Biology

Saturated fatty acids are degraded by the stepwise  reactions of B oxidation, producing acetyl-CoA. Under aerobic conditions, how many ATP molecules would be produced as a consequence of removal of each acetyl-CoA?

TLS Online TPP Program

#Question id: 996

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is (are) true of the oxidation of 1 mol of palmitate (a 16-carbon saturated fatty acid; 16:0) by the B-oxidation pathway, beginning with the free fatty acid in the cytoplasm?

1. Activation of the free fatty acid requires the equivalent of two ATPs.

2. Inorganic pyrophosphate (PPi) is produced.

3. Carnitine functions as an electron acceptor.

4. 8 mol of FADH2 are formed.

5. 8 mol of acetyl-CoA are formed.

6. There is no direct involvement of NAD+.