TLS Online TPP Program

#Question id: 892


Assisted protein folding is mediated by a group of proteins known as chaperons, which of the following statements is incorrectly reperesents chaperon activity;

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. chaperon help to fold, unfolded and partially folded polypeptide chains to disrupt the improper association of exposed hydrophobic segments

  2. All molecular chaperones operate by binding to an unfolded or aggregated protein’s, and molecular chaperon donot requires ATP for their activity

  3. molecular chaperones function to lift folding polypeptides out of the false minima in their folding funnels

  4. molecular chaperones were first described as heat shock proteins (Hsp) because their rate of synthesis is increased at elevated temperatures

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TLS Online TPP Program

#Question id: 31234

#Unit 2. Cellular Organization

Failure of which surveillance mechanism is most likely to result in non-dysjunction of chromosomes?

TLS Online TPP Program

#Question id: 3312

#Unit 11. Evolution and Behavior

Hardy-Weinberg equilibrium, the frequencies of the two alleles A1 and A2 is 0.4 and 0.6. When you consider A2 is dominant allele of genetic disorder. The frequency of defected individuals, in population size 1000 is

TLS Online TPP Program

#Question id: 11724

#Unit 6. System Physiology – Plant

At the subcellular level, starch is stored in amyloplasts in the endosperm of cereals. Two enzymes responsible for initiating starch degradation are α- and β-amylase

a) α-Amylase hydrolyzes starch chains internally to produce oligosaccharides consisting of α(1,4)-linked glucose residues

b) β-Amylase degrades these oligosaccharides from the ends to produce maltose, a disaccharide

c) α-Amylase degrades these oligosaccharides from the ends to produce maltose, a disaccharide

d)  α-Amylase hydrolyzes starch chains internally to produce oligosaccharides consisting of  β(1,4)-linked glucose residues

e) β-Amylase also converts maltose to glucose

Which of the following combination from the above statements is correct?

TLS Online TPP Program

#Question id: 12384

#Unit 7. System Physiology – Animal

To evaluate kidney function in a 45-year-old woman with type II diabetes, you ask her to collect her urine over 24 hours. She collects 3600 ml of urine in that period. The clinical laboratory returns the following results after analyzing the patient’s urine and plasma samples: plasma creatinine = 4 mg/dL, urine creatinine = 32 mg/dL, plasma potassium = 5 mmol/L, and urine potassium = 10 mmol/L.
What is this patient’s approximate GFR, assuming that she collected all her urine in the 24-hour period?

TLS Online TPP Program

#Question id: 4406

#Unit 3. Fundamental Processes

An electrophoretic mobility shift assay (EMSA) was conducted to check for the binding of TFIIB to a segment of a DNA promoter region. Which of the following approaches could be used to confirm that TFIIB is indeed binding?