Practice Questions

TLS Online TPP Program

#Question id: 12492

A young man with phenylketonuria, who was successfully treated following diagnosis on newborn screening, is planning to start a family with his healthy, unaffected, and unrelated partner, who has no family history of phenylketonuria . Phenylketonuria shows autosomal recessive inheritance with an incidence of 1 in 10 000. Assume that the population is in Hardy-Weinberg equilibrium. Which of the following is correct?

#Unit 8. Inheritance Biology

The probability that his partner is a carrier is 1 in 100.
The probability that the man will transmit a mutant allele to his first child is 1 in 2.
The probability that his partner will transmit a mutant allele to their first child is 1 in 50.
The probability that their first child will be affected is 1 in 100.