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#Question id: 12492


A young man with phenylketonuria, who was successfully treated following diagnosis on newborn screening, is planning to start a family with his healthy, unaffected, and unrelated partner, who has no family history of phenylketonuria . Phenylketonuria shows autosomal recessive inheritance with an incidence of 1 in 10 000. Assume that the population is in Hardy-Weinberg equilibrium. Which of the following is correct?

#Unit 8. Inheritance Biology
  1. The probability that his partner is a carrier is 1 in 100.
  2. The probability that the man will transmit a mutant allele to his first child is 1 in 2.
  3. The probability that his partner will transmit a mutant allele to their first child is 1 in 50.
  4. The probability that their first child will be affected is 1 in 100.
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#Question id: 3634

#Unit 8. Inheritance Biology

In the pearl millet plant, color is determined by three alleles at a single locus: Rp1 (red), Rp2 (purple), and Rp3 (green). Red is dominant over purple and green, and purple is dominant over green (Rp1 >Rp2 >Rp3). Which of the following parental cross would produce ½ had red, ¼ purple, ¼ green?

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#Question id: 3635

#Unit 8. Inheritance Biology

In the multiple allele series that determines coat color in rabbits, c+codes for agouti, cch for chinchilla and ch for Himalayan. Dominance is in the order c+>cch>ch. In a cross of c+/cch X cch/ch, what proportion of progeny will be chinchilla?

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#Question id: 3636

#Unit 8. Inheritance Biology

A man with type A blood group marries a woman with type A blood group. Their first child has type O blood. What is the genotype of the Man, proportion of his gametes are expected to contain the IA allele, and probability that their next child will have type A blood respectively:

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#Question id: 3637

#Unit 8. Inheritance Biology

Parents that are homozygous for different mutations a, b and c are crossed, producing offspring that are heterozygous as following

aa X bb        =  ab  (X)          

 bb X cc         =  bc  (Y)

aa X cc          =   ac  (Z)

If a and b belong to same locus but b and c belong to different locus then phenotype of heterozygote

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#Question id: 3638

#Unit 8. Inheritance Biology

Four different mutant lines showing similar phenotype were identified from a genetic screen. When genetic crosses among these mutants were carried out, the first mutant was found to complement the second, third and fourth mutant lines. However, no other complementation groups do the four mutant lines belongs to?

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#Question id: 3639

#Unit 3. Fundamental Processes

Replication of a bacterial chromosome normally starts at a fixed point called: