TLS Online TPP Program

#Question id: 4143


It is possible to convert the Cys that is a part of Cys-tRNACys to Ala by a catalytic reduction.  If the resulting Ala-tRNACys were added to a mixture of (1) ribosomes, (2) all the other tRNAs and amino acids, (3) all of the cofactors and enzymes needed to make protein in vitro, and (4) mRNA for hemoglobin, where in the newly synthesized hemoglobin would the Ala from Ala-tRNACys be incorporated?

#Part-A Aptitude & General Biotechnology
  1. Nowhere; this is the equivalent of a nonsense mutation

  2. Wherever Ala normally occurs

  3. Wherever Cys normally occurs

  4. Wherever either Ala or Cys normally occurs

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TLS Online TPP Program

#Question id: 4741

#Part-A Aptitude & General Biotechnology

The F2 progeny from a particular cross exhibit a modified dihybrid ratio of 9 : 7 (instead of 9 : 3 : 3 : 1). What phenotypic ratio would be expected from a testcross of the F1?

TLS Online TPP Program

#Question id: 4742

#Part-A Aptitude & General Biotechnology

In birds, sex is determined by a ZW chromosome scheme. Males are ZZ and females are ZW. A recessive lethal allele that causes death of the embryo is sometimes present on the Z chromosome in pigeons. What would be the sex ratio in the offspring of a cross between a male that is heterozygous for the lethal allele and a normal female?

TLS Online TPP Program

#Question id: 4742

#Part-B Specialized Branches in Biotechnology

In birds, sex is determined by a ZW chromosome scheme. Males are ZZ and females are ZW. A recessive lethal allele that causes death of the embryo is sometimes present on the Z chromosome in pigeons. What would be the sex ratio in the offspring of a cross between a male that is heterozygous for the lethal allele and a normal female?

TLS Online TPP Program

#Question id: 4743

#Part-A Aptitude & General Biotechnology

Ectrodactyly is an autosomal dominant trait that causes missing middle fingers (lobster claw malformation). A grandfather and grandson both have ectrodactyly, but the intervening father has normal hands by x-ray. Which of the following terms applies to this family?

TLS Online TPP Program

#Question id: 4743

#Part-B Specialized Branches in Biotechnology

Ectrodactyly is an autosomal dominant trait that causes missing middle fingers (lobster claw malformation). A grandfather and grandson both have ectrodactyly, but the intervening father has normal hands by x-ray. Which of the following terms applies to this family?

TLS Online TPP Program

#Question id: 4744

#Part-A Aptitude & General Biotechnology

Assume that long ear lobes in humans are an autosomal dominant trait that exhibits 50% penetrance. A person who is heterozygous for long ear lobes mates with a person who is homozygous for normal ear lobes. What is the probability that their first child will have long ear lobes.