TLS Online TPP Program

#Question id: 532


In glycolysis, fructose 1,6-bisphosphate is converted to two products with a standard free-energy change (DG'°) of 23.8 kJ/mol.  Under what conditions (encountered in a normal cell) will the free-energy change (DG) be negative, enabling the reaction to proceed to the right?

#Part-B Specialized Branches in Biotechnology
  1. If the concentrations of the two products are high relative to that of fructose 1,6-bisphosphate.

  2. The reaction will not go to the right spontaneously under any conditions because the DG'° is positive.

  3. Under standard conditions, enough energy is released to drive the reaction to the right.

  4. When there is a high concentration of fructose 1,6-bisphosphate relative to the concentration of products.

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TLS Online TPP Program

#Question id: 850

#Part-B Specialized Branches in Biotechnology

The experimental inverse of protein structure prediction, has provided insights into protein folding and stability. Protein design attempts to construct an amino acid sequence that will form a structure such as a sandwich of β sheets or a bundle of α helices;

TLS Online TPP Program

#Question id: 852

#Part-B Specialized Branches in Biotechnology

.________ enzyme revealed the relation between the amino acid sequence of a protein and its conformation.

TLS Online TPP Program

#Question id: 854

#Part-B Specialized Branches in Biotechnology

Many conditions including type 2 diabetes, Alzheimer  disease, Huntington disease and parkinson disease are associated with the misfolding mechanism a soluble protein that is normally secreted from the cell is secreted in the missfold state and converted into an insoluble extracellular fibre the diseases are correctly referred to as

TLS Online TPP Program

#Question id: 857

#Part-B Specialized Branches in Biotechnology

The aggregation of nonpolar side chains in the interior of a protein is favored by

TLS Online TPP Program

#Question id: 859

#Part-B Specialized Branches in Biotechnology

Which one statement is incorrect about ATG genes;

TLS Online TPP Program

#Question id: 861

#Part-B Specialized Branches in Biotechnology

Alexander Varshavsky discovered, the half-lives of many cytoplasmic proteins vary with the identities of their N-terminal residues via the so-called N-end rule:-

A. Destabilizing N-terminal residues Asp, Arg, Leu, Lys, and Phe have half-lives of

i. Only 2 to 3 minutes,

B. Stabilizing N-terminal residues Ala, Gly, Met, Ser, Thr, and Val have half-lives of

ii. >10 hours in prokaryotes

iii. >20 hours in eukaryotes.