TLS Online TPP Program

#Question id: 12492


A young man with phenylketonuria, who was successfully treated following diagnosis on newborn screening, is planning to start a family with his healthy, unaffected, and unrelated partner, who has no family history of phenylketonuria . Phenylketonuria shows autosomal recessive inheritance with an incidence of 1 in 10 000. Assume that the population is in Hardy-Weinberg equilibrium. Which of the following is correct?

#Part-A Aptitude & General Biotechnology
  1. The probability that his partner is a carrier is 1 in 100.
  2. The probability that the man will transmit a mutant allele to his first child is 1 in 2.
  3. The probability that his partner will transmit a mutant allele to their first child is 1 in 50.
  4. The probability that their first child will be affected is 1 in 100.
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TLS Online TPP Program

#Question id: 12069

#Part-B Specialized Branches in Biotechnology

Post-tetanic facilitation is thought to be the result of

TLS Online TPP Program

#Question id: 12069

#Part-A Aptitude & General Biotechnology

Post-tetanic facilitation is thought to be the result of

TLS Online TPP Program

#Question id: 12173

#Part-A Aptitude & General Biotechnology

Female with only one X chromosome is a characteristics of individual with

TLS Online TPP Program

#Question id: 12173

#Part-B Specialized Branches in Biotechnology

Female with only one X chromosome is a characteristics of individual with

TLS Online TPP Program

#Question id: 12187

#Part-B Specialized Branches in Biotechnology

How cells know whether sister kinetochores are properly attached to the mitotic spindle?

TLS Online TPP Program

#Question id: 12188

#Part-B Specialized Branches in Biotechnology

The series of events by which APC/C promotes the separation of sister chromatids at anaphase.
A. all the kinetochores have attached to spindle microtubules and the spindle apparatus is properly assembled and oriented.
B. Cdc20 specificity factor associated with APC/C directs it to ubiquitinylate securin and mitotic cyclins. 
C. A protease known as separase cleaves the cohesin subunit Scc1 (Rad21), breaking the protein circles linking sister chromatids.
D. anaphase begins as poleward force exerted on the kinetochores moves the split sister chromatids toward opposite spindle poles.
E. Following securin degradation and a decrease in mitotic CDK activity.
Which of the following series is correct?