T-Cell Development

1.Commitment

2.antigen receptor gene rearrangements

3.The selection and expansion of cells (β-selection

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They are pAPCs

Have surface marker  CD19

Antibodies at surface of b cell – IgM, IgD

Cause humoral immunity or antibodies mediated immunity

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#Section 2: General Biology

Surface protein on B cell

CR2(CR21)

CD19

TAPA-1(CD81)

mIg 

Igα/ Igβ

(CD79a and CD79B)

TLR

CD40

B7(CD80/86)

ICAM-1

MHC-1 and 2 both

CD 22

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#Section 2: General Biology

Step involve in formation of mature B-cell

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#Section 2: General Biology

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#Section 2: General Biology

B cell Development

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#Section 2: General Biology