Regulation and function of T helper subtypes

TLS Online TPP Program

#Id: 8343

#Section 3: Genetics, Cellular and Molecular Biology

formin family members have two adjacent domains:

FH1- rich in proline, landing site for profilin–ATP–G-actin

FH2 - form a dimer and nucleate filament assembly

TLS Online TPP Program

#Id: 8967

#Section 3: Genetics, Cellular and Molecular Biology

Nonsynonymous mutations, on the other hand, alter the amino acid sequence of the protein and in many cases are detrimental to the fitness of the organism, so most of these mutations are eliminated by natural selection.

TLS Online TPP Program

#Id: 10366

#Section 2: General Biology

Class I MHC, glycoproteins expressed on the surface of nearly all nucleated cells; the major function of the class I is presentation of endogenous peptide antigens to CD8+ T cells.

TLS Online TPP Program

#Id: 8162

#Section 3: Genetics, Cellular and Molecular Biology

For selective export of certain membrane proteins from the ER contain a di-acidic sorting signal (Asp-X-Glu, or DXE), which binds to the Sec24 subunit of the COPII

TLS Online TPP Program

#Id: 8620

#Section 3: Genetics, Cellular and Molecular Biology

A second class of CKIs found in metazoan cells is the Cip/Kip family of CKIs, consists of three proteins—p21CIP, p27KIP1, and p57KIP2.