TLS Online TPP Program

#Id: 10329

#Section 2: General Biology

Binding of the extracellular TCR domain to a MHC-peptide complex triggers activation of ZAP70 protein tyrosine kinases attached to the cytosolic domains of the two adjacent ζ chains. 

TLS Online TPP Program

#Id: 8337

#Section 3: Genetics, Cellular and Molecular Biology

Profilin – G-actin nucleotide exchange (ADP to ATP) 

Cofilin – F-actin disassembly

Thymosin B-4 – G-actin monomer sequestering

TLS Online TPP Program

#Id: 7762

#Section 2: General Biology

In a covalent bond, electrons are shared between atoms. In an ionic bond, electrons are transferred between atoms.

TLS Online TPP Program

#Id: 8415

#Section 3: Genetics, Cellular and Molecular Biology

Dilated cardiomyopathy

Minor missense mutations in the cardiac actin gene

TLS Online TPP Program

#Id: 8391

#Section 3: Genetics, Cellular and Molecular Biology

When the Ca2+ level rises, Ca2+ binds CaM.