One individual, however, expresses only a small number of these molecules—up to six different class I molecules and 12 or more different class II molecules.

TLS Online TPP Program

#Id: 8197

#Section 3: Genetics, Cellular and Molecular Biology

Zellweger syndrome

Autosomal recessive Mutations in any of a dozen different peroxins, the most common being Pex1, cause an impairment in peroxisomal protein import.

TLS Online TPP Program

#Id: 8196

#Section 3: Genetics, Cellular and Molecular Biology

The AAA ATPases Pex1 and Pex6 complex use the energy from ATP hydrolysis and causing the detachment of Pex 5 receptors into cytosol.

TLS Online TPP Program

#Id: 8195

#Section 3: Genetics, Cellular and Molecular Biology

A Pex 2, Pex 10, and Pex 12 complex embedded in the peroxisomal membrane transfers Ubiquitin to two embedded Pex 5 receptors.

TLS Online TPP Program

#Id: 8194

#Section 3: Genetics, Cellular and Molecular Biology

After assembly of the matrix protein-Pex5-Pex14 complex, the matrix protein dissociates from Pex5 and is released into the peroxisomal matrix.

TLS Online TPP Program

#Id: 8193

#Section 3: Genetics, Cellular and Molecular Biology

Pex5 forms a multimeric complex with the Pex14 receptor located on the peroxisomal membrane. 

TLS Online TPP Program

#Id: 8192

#Section 3: Genetics, Cellular and Molecular Biology

Catalase, are synthesized as precursors with PTS1

Thiolase, are synthesized as precursors with PTS2