The G1 cyclin-CDK complex (Cln3-CDK in yeast) stimulates the formation of G1/S phase cyclin-CDKs, which initiate bud formation, centrosome duplication, and DNA replication.

TLS Online TPP Program

#Id: 8849

#Section 3: Genetics, Cellular and Molecular Biology

Phosphorylation of MCM helicase activators by G1/S phase CDKs and S phase CDKs, prevents reloading of MCM helicases (ensuring that replication from each origin occurs only once during each cell cycle)

TLS Online TPP Program

#Id: 8090

#Section 2: General Biology

In triacylglycerols, glycerophospholipids, galactolipids, and sulfolipids, the alkyl groups are fatty acids in ester linkage. 

TLS Online TPP Program

#Id: 9285

#Section 2: General Biology

O2‐sensitive hemoprotein kinase FixL controls a regulatory cascade that activates transcription of nitrogen fixation genes

TLS Online TPP Program

#Id: 8226

#Section 3: Genetics, Cellular and Molecular Biology

I-cell disease

• almost all of the hydrolytic enzymes are missing from the lysosomes of many cell types.

• mis-sorting has been traced to a defective or missing GlcNAc phosphotransferase.

TLS Online TPP Program

#Id: 8223

#Section 3: Genetics, Cellular and Molecular Biology

Retromer

a coat protein complex specialized for endosome-to-TGN transport, recycle the M6P receptor to the TGN