In vertebrates, Rb is the major guardian of the cell cycle, integrating information about DNA damage and cell growth

TLS Online TPP Program

#Id: 8405

#Section 3: Genetics, Cellular and Molecular Biology

Muscle contraction depends on two processes that consume enormous amounts of ATP: 

1. Filament sliding, driven by the ATPase of the myosin

2. Ca2+ pumping, driven by the Ca2+ ATPase

TLS Online TPP Program

#Id: 10377

#Section 2: General Biology

TLS Online TPP Program

#Id: 8846

#Section 3: Genetics, Cellular and Molecular Biology

In budding yeast CKI p27 = Sic1 in metazoans

TLS Online TPP Program

#Id: 9216

#Section 3: Genetics, Cellular and Molecular Biology

Ne = Male + Female  (when both are equal)

Ne = 4 × n(male) × n(female)/n(male)+n(female) 

(When both unequal Ne is smaller than then sum of both)

TLS Online TPP Program

#Id: 8879

#Section 3: Genetics, Cellular and Molecular Biology

This combination of two positive feedback loops:

one that activates a CDK1 activator (Cdc25C)

one that inhibits a CDK1 inhibitor (Wee1)

results in the abrupt and irreversible transition from G2 into mitosis.