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Focal adhesion
Function- Shape, signaling, force transmission, cell movement

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In the absence of Wnts,
“free” β-catenin are targeted for degradation by a cytosolic destruction complex that is held together by the tumor suppressor protein Axin.

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During late anaphase, telophase and G1, APC/C bound to Cdh1 targets B type cyclins and geminin for degradation.

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The triterpenes are C30 terpenes and include squalene and lanosterol, two of the precursors of cholesterol


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NOD1 also provides protection against the intracellular protozoan parasite Trypanosoma  cruzi,
NOD2 activates responses to some viruses, including influenza.

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Darwin’s evolutionary theory- Common descent

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