Excreted S1P provokes many different cell and tissue effects, among them inflammation in allergic reactions, cell proliferation, angiogenesis, malignant transformation, and movement and migration of certain cells.

TLS Online TPP Program

#Id: 9621

#XL - T Zoology

Kinase domains typically contain two regions:

N and C lobes

TLS Online TPP Program

#Id: 9086

#XL - T Zoology

A1 associates with ARF6, a small G protein in host cells which are accessible only when ARF6 is in its active (GTP-bound) form. 

TLS Online TPP Program

#Id: 10295

#XL - Q Biochemistry

Allelic exclusion - Once allele’s functional protein is generated, rearrangement at the other allele is shut down

TLS Online TPP Program

#Id: 9735

#XL - R Botany

Members of the Brassicales produce glucosinolates—sulfur-containing organic compounds derived from glucose and an amino acid—as their major defensive secondary metabolites

TLS Online TPP Program

#Id: 10330

#XL - Q Biochemistry

The idea behind CARs was to engineer the T-cell receptor to trigger activation of ZAP70 in response to the presence of a tumor-specific antigen rather than the MHC peptide complex.