Phosphorylation of PKA at threonine-197 leads to conformational change in the activation loop, that promotes binding of both ATP and its substrate proteins.

PKA can autophosphorylate itself on T197

TLS Online TPP Program

#Id: 8156

#XL - Q Biochemistry

Two different kinds of sorting signals:

Membrane cargo proteins carry cytoplasmic sorting signals

Soluble cargo proteins carry luminal sorting signals

TLS Online TPP Program

#Id: 8923

#XL - T Zoology

Surveillance mechanisms known as checkpoint pathways responsible for the extraordinarily high fidelity of cell division, ensuring that each daughter cell receives the correct number of accurately replicated chromosomes

TLS Online TPP Program

#Id: 8883

#XL - R Botany

Once mitotic CDKs are activated at the end of G2 , they phosphorylate specific serine residues in all 3 nuclear lamins.

TLS Online TPP Program

#Id: 9036

#XL - T Zoology

The affinity of a signal molecule’s binding to its receptor is quantified by the dissociation constant for binding (Kd).

TLS Online TPP Program

#Id: 10694

#XL - R Botany

Cortex ;

Consist of thin walled parenchymatous cells with intercellular spaces. Innermost layer of cortex is known as Endodermis