Bateman’s principle

In most cases, it is the male’s secondary sexual traits that are exaggerated.

This shows that sexual selection is more common and intense on males than females

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Planar Cell Polarity 

direct cells to divide in the same plane (rather than forming upper and lower tissue compartments) and to move within that same plane

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The Wnt-Ca2+ pathway is initiated by Frizzled receptors activating a classical G protein-coupled signaling pathway.

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In Wnt-Ca2+ pathway, Wnt binding to the receptor protein possibly Ryk, alone or in concert with Frizzled.

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Frizzled-G protein signaling activates PLC-beta, which cleaves PIP2 into DAG and IP3.

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Wnt/calcium pathway leads to the release of calcium stored within cells, and calcium acts as an important secondary messenger to modulate the function of many downstream targets.