Perception of MAMPs or DAMPs by cell surface PRRs is called Pathogen Triggered Immunity

TLS Online TPP Program

#Id: 8924

#XL - T Zoology

DNA damage response system

halts cell cycle progression and

recruits DNA repair machinery

when DNA is compromised

TLS Online TPP Program

#Id: 8925

#XL - T Zoology

The protein kinases DNA-PK, ATM, and ATR are activated at sites of damaged DNA

TLS Online TPP Program

#Id: 8926

#XL - T Zoology

ATR activated by single-stranded DNA breaks.

TLS Online TPP Program

#Id: 8927

#XL - T Zoology

ATM and DNA-PK are specifically activated by double-strand breaks

TLS Online TPP Program

#Id: 8928

#XL - T Zoology

ATM and ATR, activate a triad of related protein kinases: Chk1, Chk2, and MK2

TLS Online TPP Program

#Id: 8929

#XL - T Zoology

Chk1, Chk2, and MK2

cause cell cycle arrest by inhibiting Cdc25

stabilizing the transcription factor p53, which induces the transcription of CKI p21