Dissociation of cytosolic complex leads to the stabilization of the full-length Ci, which moves into the

nucleus, displaces the repressor Ci75 from the promoter of target genes, and induces expression of target genes.

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#Id: 982

#Unit 5. Developmental Biology

IGFs and FGFs in the anterior region, Initiate the receptor tyrosine kinase (RTK) signalling inhibit BMPs and Wnts pathways

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#Id: 8967

#Unit 11. Evolution and Behavior

Nonsynonymous mutations, on the other hand, alter the amino acid sequence of the protein and in many cases are detrimental to the fitness of the organism, so most of these mutations are eliminated by natural selection.

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#Id: 6285

#Unit 3. Fundamental Processes

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#Id: 5680

#Unit 7. System Physiology – Animal

A unique electrogenic K + pump in the stria vascularis accounts for the fact that the scala media is electrically positive by 85 mV relative to the scala vestibuli

and scala tympani

 

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#Id: 6220

#Unit 12. Applied Biology

Adeno-associated vectors (AAV) Adeno-associated viruses (AAVs) are a group of small, single-stranded DNA viruses. The insert size for AAV is 4.5 kb, with the advantage of long-term gene expression as they integrate into chromosomal DNA.