Gap junctions permit the passage of molecules as large as 1.2 nm in diameter (molecules smaller than 1200 Da).

TLS Online TPP Program

#Id: 1272

#Unit 7. System Physiology – Animal

Aldosterone has three actions on the late distal tubule and collecting ducts of the kidney: 

Increases Na+ reabsorption

Increases K+ secretion

Increases H+ secretion

TLS Online TPP Program

#Id: 1273

#Unit 7. System Physiology – Animal

ACTH stimulates the synthesis and secretion of cortisol by the activation of adenylyl cyclase via Gs.

TLS Online TPP Program

#Id: 1274

#Unit 7. System Physiology – Animal

Angiotensin II stimulates the synthesis and secretion of aldosterone by the activation of phospholipase C via Gq. 

TLS Online TPP Program

#Id: 1275

#Unit 7. System Physiology – Animal

Important effect of cortisol, Decrease translocation of GLUT4 to the cell membrane.

TLS Online TPP Program

#Id: 1276

#Unit 7. System Physiology – Animal

Cortisol induces the synthesis of lipocortin, an inhibitor of the enzyme PLA2. 

TLS Online TPP Program

#Id: 1277

#Unit 7. System Physiology – Animal

Cortisol inhibits the production of interleukin-2 and the proliferation of T lymphocytes.