A mutation, valine to glutamine in the TM region of the HER2 receptor causes dimerization of the receptor, even in the absence of the ligand, transforming it into the oncoprotein NEU, a constitutively active protein tyrosine kinase.

TLS Online TPP Program

#Id: 4476

#Unit 13. Methods in Biology

Differential-interference-contrast (DIC) microscopy based on splitting of light into two and then recombining them to observe their interference pattern.

TLS Online TPP Program

#Id: 10344

#Unit 4. Cell Communication and Cell Signaling

B- cell maturation

TLS Online TPP Program

#Id: 1697

#Unit 4. Cell Communication and Cell Signaling

ZnA and ZnB on RAG1 are regions of the proteins that form zinc fingers, elongated protein domains stabilized by the coordination of a Zn ion.

TLS Online TPP Program

#Id: 6891

#Unit 3. Fundamental Processes

The Xist transcript is regulated in a negative manner by Tsix, its antisense partner.

TLS Online TPP Program

#Id: 8693

#Unit 1. Molecules and their Interaction Relevant to Biology

Gluconeogenesis occurs in all animals, plants, fungi, and microorganisms. The reactions are essentially the same in all tissues and all species.

The important precursors of glucose in animals are three-carbon compounds such as lactate, pyruvate, and glycerol, as well as certain amino acids