TLS Online TPP Program

#Id: 8318

#Unit 2. Cellular Organization

Nucleation phase 

Two G-actin molecules bind relatively weakly to each other, but addition of a third actin monomer to form a trimer makes the entire group more stable, acts as a nucleus for polymerization.

TLS Online TPP Program

#Id: 8319

#Unit 2. Cellular Organization

Nucleation phase 

Lag period (Time taken for nucleation) Rate-limiting Step.

TLS Online TPP Program

#Id: 8320

#Unit 2. Cellular Organization

The lag phase can be reduced or abolished entirely by adding premade nuclei.

TLS Online TPP Program

#Id: 8321

#Unit 2. Cellular Organization

Elongation phase

short oligomer rapidly increases in length by the addition of actin monomers to both of its ends, causing filament elongation

TLS Online TPP Program

#Id: 8322

#Unit 2. Cellular Organization

Steady-state phase

G-actin monomers exchange with subunits at the filament ends, but there is no net change in the total length of filaments.

TLS Online TPP Program

#Id: 8323

#Unit 2. Cellular Organization