Pointers

  1. Home
  2. Free Resources
  3. Pointers
  4. 1579
TLS Online TPP Program

#Id: 1579

Notum, a hydrolase that associates with glypican and then cleaves off Wnt’s attached lipids in a process of deacylation or delipidation.

#Unit 4. Cell Communication and Cell Signaling #Signal transduction pathways #Part B Pointers
PYQ Links
  1. PYQ 1
Extensive Links
  1. Link 1
More Pointers
TLS Online TPP Program

#Id: 8334

#Unit 2. Cellular Organization

Phalloidin 
isolated from Amanita phalloides, binds at the interface between subunits in F-actin, locking adjacent subunits together and preventing depolymerization.
TLS Online TPP Program

#Id: 8335

#Unit 2. Cellular Organization
TLS Online TPP Program

#Id: 8336

#Unit 2. Cellular Organization

Actin filament treadmilling is accelerated by:

Profilin and Cofilin
TLS Online TPP Program

#Id: 8337

#Unit 2. Cellular Organization

Profilin – G-actin nucleotide exchange (ADP to ATP) 
Cofilin – F-actin disassembly
Thymosin B-4 – G-actin monomer sequestering
TLS Online TPP Program

#Id: 8338

#Unit 2. Cellular Organization

Profilin can bind proteins with sequences rich in proline residues at the same time it is bound to actin.
TLS Online TPP Program

#Id: 8339

#Unit 2. Cellular Organization

Filament capping proteins:

CapZ blocks (+)end Tropomodulin blocks (-)end