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TLS Online TPP Program

#Id: 1732

The early response occurs within minutes of allergen exposure and results from the release of histamine, leukotrienes, and prostaglandins from local mast cells.

#Unit 4. Cell Communication and Cell Signaling #Hypersensitivity and autoimmunity #Part B Pointers
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TLS Online TPP Program

#Id: 9892

#Unit 4. Cell Communication and Cell Signaling

Pattern recognition
Families of PRRs (TLRs, CLRs, RLRs, and NLRs) recognize a wide variety of PAMP (and DAMP) ligands.
TLS Online TPP Program

#Id: 9893

#Unit 4. Cell Communication and Cell Signaling

Toll-Like Receptors Recognize Many Types of Pathogen Molecules - Vertebrate Toll-like receptors  are dimers of chains with extracellular leucine-rich (LRR) domains that bind PAMPs and DAMPs. 
TLS Online TPP Program

#Id: 9894

#Unit 4. Cell Communication and Cell Signaling
TLS Online TPP Program

#Id: 9895

#Unit 4. Cell Communication and Cell Signaling
TLS Online TPP Program

#Id: 9896

#Unit 4. Cell Communication and Cell Signaling
TLS Online TPP Program

#Id: 9897

#Unit 4. Cell Communication and Cell Signaling

C-type lectin receptor (CLR)
CLRs are plasma membrane receptors and generally recognize carbohydrate components of fungi, mycobacteria, viruses, parasites, and some allergens.