Broad-sense heritability range from 0 to 1.

0 =all of the phenotypic variance results from environmental variation.

1 =all of the phenotypic variance results from differences in genotype.

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#Unit 3. Fundamental Processes

rho mutants are usually leaky

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#Unit 4. Cell Communication and Cell Signaling

The second phase of T-cell development

1.Positive selection: Selection for those cells whose T-cell receptors engage self-MHC.

2.Negative selection: Selection against those cells whose T-cell receptors bind too strongly to self-peptide/MHC combinations.

3.Lineage commitment: Commitment of thymocytes to effector cell lineages, including CD4 helper or CD8 cytotoxic populations

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#Unit 4. Cell Communication and Cell Signaling

Carcinogens

1. Environmental DNA-damaging agents

2.Prevent DNA damage from being repaired with high fidelity

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#Id: 5685

#Unit 7. System Physiology – Animal

The posterior lobe hormones are nanopeptides with a disulfide ring at one end

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#Id: 9478

#Unit 4. Cell Communication and Cell Signaling

SOCS box, 

Recruits E3 ubiquitin ligases that polyubiquitinylate the receptor and the JAK kinase & marks the proteins for destruction by a proteasome