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TLS Online TPP Program

#Id: 2110

Deletions are lethal in the homozygous state because all copies of any essential genes located in the deleted region are missing.

#Unit 8. Inheritance Biology #Deletion #Part B Pointers
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TLS Online TPP Program

#Id: 5817

#Unit 7. System Physiology – Animal

The zona glomerulosa is controlled via; Renin-angiotensin- aldosterone system
TLS Online TPP Program

#Id: 5818

#Unit 7. System Physiology – Animal

Aldosterone has three actions on the late distal tubule and collecting ducts of the kidney:
TLS Online TPP Program

#Id: 5819

#Unit 7. System Physiology – Animal

The renal epithelial cells express the enzyme 11β-HSD2, which prevent cortisol from activating mineralocorticoid receptors.
TLS Online TPP Program

#Id: 5820

#Unit 7. System Physiology – Animal

Apparent mineralocorticoid excess (AME)

11β-hydroxysteroid dehydrogenase type 2 is inhibited or absent
TLS Online TPP Program

#Id: 5821

#Unit 7. System Physiology – Animal

ACTH stimulates the synthesis and secretion of cortisol by the activation of adenylyl cyclase via Gs.
TLS Online TPP Program

#Id: 5822

#Unit 7. System Physiology – Animal

Angiotensin II stimulates the synthesis and secretion of aldosterone by the activation of phospholipase C via Gq