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TLS Online TPP Program

#Id: 2279

Consensus Sequences


#Unit 3. Fundamental Processes #Eukaryotic transcription factors and machinery #Part B Pointers
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TLS Online TPP Program

#Id: 3011

#Unit 3. Fundamental Processes

The E. coli SSB is a tetramer; eukaryotic SSB (also known as RPA) is a trimer.
TLS Online TPP Program

#Id: 3012

#Unit 3. Fundamental Processes

A helicase usually initiates unwinding at a single-stranded region adjacent to a duplex. Note that it cannot unwind a segment of duplex DNA; it can only continue to unwind a sequence that has been started.
TLS Online TPP Program

#Id: 3013

#Unit 3. Fundamental Processes

Helicase, It may function with a particular polarity, preferring single-stranded DNA with a 3 ' end (3'-5' helicase) or with a 5' end ( 5 '-3' helicase).
TLS Online TPP Program

#Id: 3014

#Unit 3. Fundamental Processes

E. coli SSB is a tetramer of 74 kD that binds single-stranded DNA cooperatively. The significance of the cooperative mode of binding.
TLS Online TPP Program

#Id: 3015

#Unit 3. Fundamental Processes

E. coli SSB- Note that this protein is not a DNA-unwinding protein; its function is to stabilize DNA that is already in the single-stranded condition
TLS Online TPP Program

#Id: 3016

#Unit 3. Fundamental Processes

ssb mutants have a quick stop phenotype, and are defective in repair and recombination as well as in replication.