Input of energy in the form of ATP is required at several stages for the prepriming reaction, and it is required for unwinding DNA.

TLS Online TPP Program

#Id: 8284

#Unit 1. Molecules and their Interaction Relevant to Biology

During hydrophobic interaction, the non-polar molecules come together, releasing some of the ordered water molecules in the clathrate structure and thus increasing entropy.

This is a thermodynamically favourable process (dG < 0), even though it is endothermic (dH > 0) because more hydrogen bonds are broken than are made.

TLS Online TPP Program

#Id: 324

#Unit 1. Molecules and their Interaction Relevant to Biology

TLS Online TPP Program

#Id: 326

#Unit 1. Molecules and their Interaction Relevant to Biology

When blood glucose rises above 5 mM, hexokinase IV activity increases, but hexokinase I is already operating near Vmax and cannot respond to an increase in glucose concentration. 

TLS Online TPP Program

#Id: 327

#Unit 1. Molecules and their Interaction Relevant to Biology

Hexokinase IV is subject to inhibition by the reversible binding of a regulatory protein specific to liver

TLS Online TPP Program

#Id: 329

#Unit 1. Molecules and their Interaction Relevant to Biology

FBPase-1 is a gluconeogenic enzyme

TLS Online TPP Program

#Id: 333

#Unit 1. Molecules and their Interaction Relevant to Biology

Fructose 2,6-bisphosphate binds to its allosteric site on PFK-1, it increases the enzyme’s affinity for its substrate fructose 6-phosphate and reduces its affinity for the allosteric inhibitors ATP and citrate