Most capillary walls are relatively impermeable to the proteins in plasma, and the proteins exert an osmotic force of about 25 mm Hg across the capillary wall (oncotic pressure) that pulls water into the blood.

TLS Online TPP Program

#Id: 7217

#Unit 5. Developmental Biology

T cells initiate the adaptive immune response by interacting MHC on antigen-presenting cells that have been exposed to pathogens. 

TLS Online TPP Program

#Id: 7218

#Unit 5. Developmental Biology

Development of T cells from hematopoietic stem cells on bone marrow stromal cells expressing the Notch ligand

TLS Online TPP Program

#Id: 7219

#Unit 5. Developmental Biology

T-Cell Development

Commitment of hematopoietic precursors to the T cell lineage

The initiation of antigen receptor gene rearrangements

The selection and expansion of cells that have successfully rearranged one of their T-cell receptor genes (-selection). 

TLS Online TPP Program

#Id: 7220

#Unit 5. Developmental Biology

TLS Online TPP Program

#Id: 7221

#Unit 5. Developmental Biology

Time course of appearance of  thymocytes and  thymocytes during mouse fetal development.

TLS Online TPP Program

#Id: 7222

#Unit 5. Developmental Biology

Allelic exclusion Most T cells fully rearrange and express a TCR chain from only one of their two TCR alleles.