Unbalanced gene dosage leads to developmental abnormalities.

TLS Online TPP Program

#Id: 6983

#Unit 5. Developmental Biology

Two types of Stem Cell division:

Symmetric cell division

Asymmetric cell division

TLS Online TPP Program

#Id: 6984

#Unit 5. Developmental Biology

If a stem cell divides symmetrically, have the ability to produce either two stem cells (increasing the stem cell pool by one) or two committed cells (decreasing the pool by one). This is called symmetrical renewing or symmetrical differentiating.

TLS Online TPP Program

#Id: 6985

#Unit 5. Developmental Biology

TLS Online TPP Program

#Id: 6986

#Unit 5. Developmental Biology

If a stem cell divides asymmetrically, produce two types of cells (a stem cell & a developmentally committed cell) are produced at each division, is called the single stem cell asymmetry.

TLS Online TPP Program

#Id: 6987

#Unit 5. Developmental Biology

Cell potency is a cell’s ability to differentiate into other cell types. Stem cell has the power, or potency, to produce many different types of differentiated cells.

TLS Online TPP Program

#Id: 6988

#Unit 5. Developmental Biology

The potency of a cell is an intrinsic property and is greater than or equal to its fate. Potency is described as the gene activation potential within a cell which begins with – 

Totipotency, Pluripotency, Multipotency  and finally Unipotency.