The transition from specification to determination in Drosophila is mediated by Segmentation genes.

TLS Online TPP Program

#Id: 342

#Unit 1. Molecules and their Interaction Relevant to Biology

Accumulation of alanine, which can be synthesized from pyruvate in one step, allosterically inhibits pyruvate kinase, slowing the production of pyruvate by glycolysis

TLS Online TPP Program

#Id: 344

#Unit 1. Molecules and their Interaction Relevant to Biology

The liver PK isozyme (L form) is regulated by glucagon

TLS Online TPP Program

#Id: 346

#Unit 1. Molecules and their Interaction Relevant to Biology

Pyruvate Carboxylase

a mitochondrial enzyme that requires the coenzyme biotin, converts the pyruvate to oxaloacetate

TLS Online TPP Program

#Id: 349

#Unit 1. Molecules and their Interaction Relevant to Biology

The oxaloacetate is converted to PEP by phosphoenolpyruvate carboxykinase. This Mg2+ dependent reaction requires GTP as the phosphoryl group donor.

TLS Online TPP Program

#Id: 353

#Unit 1. Molecules and their Interaction Relevant to Biology

Transketolase requires the cofactor thiamine pyrophosphate (TPP)

TLS Online TPP Program

#Id: 354

#Unit 1. Molecules and their Interaction Relevant to Biology

Acetyl-CoA and NADH are potent allosteric inhibitors of the enzyme.