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TLS Online TPP Program

#Id: 8224


Lysosomal storage diseases:
• Hurler’s disease
• Inclusion-cell disease

#Unit 2. Cellular Organization #Peroxisome & Lysosome #Part B Pointers
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TLS Online TPP Program

#Id: 383

#Unit 2. Cellular Organization

First the H3.H4 assemble into tetramer (HOI) then DNA wrapped over H3.H4 tetramer. 

TLS Online TPP Program

#Id: 384

#Unit 2. Cellular Organization

TLS Online TPP Program

#Id: 385

#Unit 2. Cellular Organization

H32-H42 tetramer accounts for the diameter of the octamer and H32-H42 tetramer alone can organize DNA in vitro into particles that display the properties of the core particle.
 

TLS Online TPP Program

#Id: 386

#Unit 2. Cellular Organization

The H32.H42 tetramer bound to DNA recruits two copies of the H2A.H2B dimer to complete the assembly of the final nucleosome


TLS Online TPP Program

#Id: 387

#Unit 2. Cellular Organization

The nucleosome has an approximate twofold axis of symmetry, called the dyad axis.


TLS Online TPP Program

#Id: 388

#Unit 2. Cellular Organization

DNA enters at 1 o’clock and exits at just short of 11 o’clock on one axis and they change time after 180 degree rotation


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