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TLS Online TPP Program

#Question id: 1262

Although MAP kinase is often activated in multicellular animals by RTKs or cytokine receptors, signaling from other receptors can activate MAP kinase in other eukaryotic cells. we consider the mating pathway in the yeast S. cerevisiae, a well-studied example of a MAP kinase cascade linked to G protein–coupled receptors (GPCRs). Which of the following statement is incorrect?

#Unit 4. Cell Communication and Cell Signaling

  1. An a haploid cell secretes the a mating factor and has GPCRs for the α factor on its cell surface; an α cell secretes the α factor and has GPCRs for the a factor. Thus each type of cell recognizes the mating factor produced by the opposite type.

  2. Ligand binding and dissociation of the G protein subunits, the membrane-tethered Gβγ subunit binds the Ste5 scaffold to the plasma membrane.

  3. Gβγ also activates Cdc24, a GAP for the Ras-like protein Cdc42; the active, GTP-bound Cdc42, in turn, binds to and activates the Ste20 kinase.

  4. Ste20 then phosphorylates and activates Ste11, which is analogous to Raf and other mammalian MEK kinase (MEKK) proteins. Ste20 thus serves as a MAPKKK kinase.

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TLS Online TPP Program

#Question id: 4642

#Unit 11. Evolution and Behavior

Which of Darwinʹs ideas had the strongest connection to Darwin having read Malthusʹs essay on human population growth?
TLS Online TPP Program

#Question id: 4643

#Unit 11. Evolution and Behavior

The treeʹs horizontal axis is a timeline that extends from 100,000 years ago to the present; the vertical axis represents nothing in particular. The labeled branch points on the tree (V—Z) represent various common ancestors. Letʹs say that only since 50,000 years ago has there been enough variation between the lineages depicted here to separate them into distinct species, and only the tips of the lineages on this tree represent distinct species.

How many separate species, both extant and extinct, are depicted in this tree?
TLS Online TPP Program

#Question id: 4644

#Unit 11. Evolution and Behavior

The treeʹs horizontal axis is a timeline that extends from 100,000 years ago to the present; the vertical axis represents nothing in particular. The labeled branch points on the tree (V—Z) represent various common ancestors. Letʹs say that only since 50,000 years ago has there been enough variation between the lineages depicted here to separate them into distinct species, and only the tips of the lineages on this tree represent distinct species.

According to this tree, what percent of the species seem to be extant (i.e., not extinct)?
TLS Online TPP Program

#Question id: 4645

#Unit 11. Evolution and Behavior

The treeʹs horizontal axis is a timeline that extends from 100,000 years ago to the present; the vertical axis represents nothing in particular. The labeled branch points on the tree (V—Z) represent various common ancestors. Letʹs say that only since 50,000 years ago has there been enough variation between the lineages depicted here to separate them into distinct species, and only the tips of the lineages on this tree represent distinct species.

Which of the five common ancestors, labeled V—Z, has given rise to the greatest number of species, both extant and extinct?
TLS Online TPP Program

#Question id: 4646

#Unit 11. Evolution and Behavior

The treeʹs horizontal axis is a timeline that extends from 100,000 years ago to the present; the vertical axis represents nothing in particular. The labeled branch points on the tree (V—Z) represent various common ancestors. Letʹs say that only since 50,000 years ago has there been enough variation between the lineages depicted here to separate them into distinct species, and only the tips of the lineages on this tree represent distinct species.

Which of the five common ancestors, labeled V—Z, has been least successful in terms of the percent of its derived species that are extant?
TLS Online TPP Program

#Question id: 4647

#Unit 11. Evolution and Behavior

The treeʹs horizontal axis is a timeline that extends from 100,000 years ago to the present; the vertical axis represents nothing in particular. The labeled branch points on the tree (V—Z) represent various common ancestors. Letʹs say that only since 50,000 years ago has there been enough variation between the lineages depicted here to separate them into distinct species, and only the tips of the lineages on this tree represent distinct species. Which of the five common ancestors, labeled V—Z, has been most successful in terms of the percent of its derived species that are extant?