Although MAP kinase is often activated in multicellular animals by RTKs or cytokine receptors, signaling from other receptors can activate MAP kinase in other eukaryotic cells. we consider the mating pathway in the yeast S. cerevisiae, a well-studied example of a MAP kinase cascade linked to G protein–coupled receptors (GPCRs). Which of the following statement is incorrect?

#Question id: 856

#Unit 1. Structure and Function of Biomolecules

Protein folding is not a completely random, trial-and-error process, This problem was first pointed out by

#Question id: 857

#Unit 1. Structure and Function of Biomolecules

The aggregation of nonpolar side chains in the interior of a protein is favored by

#Question id: 858

#Unit 1. Structure and Function of Biomolecules

Unfolded protein response (UPR)

#Question id: 859

#Unit 1. Structure and Function of Biomolecules

Which one statement is incorrect about ATG genes;

#Question id: 860

#Unit 1. Structure and Function of Biomolecules

Select true ‘T’ AND false ‘F’ about ubiquitinylation

I. These ubiquitin-like modifiers control processes as diverse as nuclear import,

II. Regulated by the ubiquitin-like modifier Sumo, and autophagy,

III. Regulated by the ubiquitin-like modifier Atg8.

IV. For a protein to be efficiently degraded, it must be linked to a chain of at least four tandemly linked ubiquitin molecules in which Lys 34 of each ubiquitin forms an isopeptide bond with the C-terminal carboxyl group of the following ubiquitin.

#Question id: 861

#Unit 1. Structure and Function of Biomolecules

Alexander Varshavsky discovered, the half-lives of many cytoplasmic proteins vary with the identities of their N-terminal residues via the so-called N-end rule:-