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TLS Online TPP Program

#Id: 8153

A second function of small GTPases in vesicle formation is in the pinching off of a completed vesicle from the parent membrane


#Section 3: Genetics, Cellular and Molecular Biology #Golgi Apparatus #Part B Pointers
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TLS Online TPP Program

#Id: 10321

#Section 2: General Biology

The tumor down regulates the expression of class I MHC proteins
TLS Online TPP Program

#Id: 10322

#Section 2: General Biology

Sometimes the tumor cells up-regulate the expression of anti-apoptotic proteins like BCL-2.
TLS Online TPP Program

#Id: 10323

#Section 2: General Biology
TLS Online TPP Program

#Id: 10324

#Section 2: General Biology

PD-1 has a structure similar to CTLA-4 and when activated negatively regulates T-cell function by inducing apoptosis of activated T cells. 
TLS Online TPP Program

#Id: 10325

#Section 2: General Biology

Monoclonal Antibodies Against Immune Checkpoint Molecules to Treat Cancers
TLS Online TPP Program

#Id: 10326

#Section 2: General Biology

Antibodies against 
CTLA-4
PD-L1 or PD-1
A CTLA-4-blocking antibody, ipilimumab