Pointers

  1. Home
  2. Free Resources
  3. Pointers
  4. 8153
TLS Online TPP Program

#Id: 8153

A second function of small GTPases in vesicle formation is in the pinching off of a completed vesicle from the parent membrane


#Section 3: Genetics, Cellular and Molecular Biology #Golgi Apparatus #Part B Pointers
PYQ Links
  1. PYQ 1
Extensive Links
  1. Link 1
More Pointers
TLS Online TPP Program

#Id: 8409

#Section 3: Genetics, Cellular and Molecular Biology

Troponin, a complex of three polypeptides, 
TN-T (tropomyosin-binding)
TN-I  (inhibitory)
TN-C (Ca2+-binding)
TLS Online TPP Program

#Id: 8408

#Section 3: Genetics, Cellular and Molecular Biology

Tropomyosin (TM) is a ropelike molecule, about 40 nm in length, binds to 7 actin subunits in an actin filament.
TLS Online TPP Program

#Id: 8406

#Section 3: Genetics, Cellular and Molecular Biology

Vertebrate skeletal muscle contraction, also depends on set of specialized accessory proteins that are closely associated with the actin thin filaments:

a) Tropomyosin

b) Troponin
TLS Online TPP Program

#Id: 8405

#Section 3: Genetics, Cellular and Molecular Biology

Muscle contraction depends on two processes that consume enormous amounts of ATP: 
1. Filament sliding, driven by the ATPase of the myosin
2. Ca2+ pumping, driven by the Ca2+ ATPase
TLS Online TPP Program

#Id: 8404

#Section 3: Genetics, Cellular and Molecular Biology

The increase in Ca2+ concentration is transient because the Ca2+ is rapidly pumped back into the SR by an abundant, Ca2+ ATPase.
TLS Online TPP Program

#Id: 8403

#Section 3: Genetics, Cellular and Molecular Biology

AP activates a  voltage gated Ca2+ channel in the T-tubule membrane, it triggers the opening of a Ca2+ -release channel in the closely associated SR membrane