The curvature of the crista junctions is due to a protein complex called MICOS (mitochondrial contact site and cristae organizing system).

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#XL - Q Biochemistry

The curvature of the crista junctions is due to a protein complex called MICOS (mitochondrial contact site and cristae organizing system).

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The cytosolic isozyme has two distinct functions. It catalyzes the conversion of citrate to isocitrate, providing the substrate for a cytosolic isocitrate dehydrogenase that generates NADPH as reducing power for fatty acid synthesis and other anabolic processes in the cytosol. It also has a role in cellular iron homeostasis.

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KDC shows Divergent evolution, in which the genes for an enzyme with one substrate specificity give rise, during evolution, to closely related enzymes with different substrate specificities but the same enzymatic mechanism.

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This reaction is catalyzed by nucleoside diphosphate kinase