ATM and DNA-PK are specifically activated by double-strand breaks

TLS Online TPP Program

#Id: 8195

#XL - Q Biochemistry

A Pex 2, Pex 10, and Pex 12 complex embedded in the peroxisomal membrane transfers Ubiquitin to two embedded Pex 5 receptors.

TLS Online TPP Program

#Id: 8194

#XL - Q Biochemistry

After assembly of the matrix protein-Pex5-Pex14 complex, the matrix protein dissociates from Pex5 and is released into the peroxisomal matrix.

TLS Online TPP Program

#Id: 8193

#XL - Q Biochemistry

Pex5 forms a multimeric complex with the Pex14 receptor located on the peroxisomal membrane. 

TLS Online TPP Program

#Id: 8192

#XL - Q Biochemistry

Catalase, are synthesized as precursors with PTS1

Thiolase, are synthesized as precursors with PTS2

TLS Online TPP Program

#Id: 8191

#XL - Q Biochemistry

PTS1 signals are recognized by the peroxin Pex5 receptor

PTS2 signals are recognized by the peroxin Pex7 receptor

Neither targeting sequence is cleaved after import.

TLS Online TPP Program

#Id: 8190

#XL - Q Biochemistry

Peroxins

Catalyse peroxisomal protein import by ATP hydrolysis.