Formation of the Wnt/Fz/LRP complex at the cell

surface causes the adaptor protein Dishevelled, to bind to Fz and Axin to bind to LRP, resulting destabilization and inactivation of the destruction complex

TLS Online TPP Program

#Id: 8043

#XL - Q Biochemistry

RS Configuration 

Atoms of higher atomic number rank above those of lower atomic number (e.g., —OH ranks above —CH3). If the first substituent atoms are identical, the priority is established by the next atom outward from the chiral center (e.g., —CH2OH takes precedence over —CH3).

TLS Online TPP Program

#Id: 8878

#XL - R Botany

At the same time that Cdc25C is being activated, mitotic CDKs and Plk1 phosphorylate Wee1, which targets it for destruction through a phosphobinding SCF protein-ubiquitin ligase. This forms positive feedback loop 2

TLS Online TPP Program

#Id: 8849

#XL - R Botany

Phosphorylation of MCM helicase activators by G1/S phase CDKs and S phase CDKs, prevents reloading of MCM helicases (ensuring that replication from each origin occurs only once during each cell cycle)

TLS Online TPP Program

#Id: 10044

#XL - T Zoology

In Notch/Delta pathway, 

signaling molecule is Delta, an integral membrane protein bound to the surface of the signaling cell.

TLS Online TPP Program

#Id: 9806

#XL - R Botany

Pr chromophore undergoes a cis–trans isomerization between carbons 15 and 16 and rotation of the C14-C15 single bond on red light exposure.