Match the correct diseases with their precursors

Disease	Protein or precursor involved in disease
1. Cystic fibrosis	a. Prion protein
2. Creutzfeldt–Jakob disease	b. CFTR
3. Familial hypercholesterolaemia	c. LDL receptor
4. fatal familial insomnia	d. β-amyloid protein
5. Alzheimer’s disease	e. β-hexosaminidase

#Question id: 4673

#Unit 3. Fundamental Processes

Lysogenic growth proceeds when

#Question id: 13122

#Unit 2. Cellular Organization

#Question id: 15305

#Unit 4. Cell Communication and Cell Signaling

#Question id: 4660

#Unit 3. Fundamental Processes

Two-component system regulating response to low Gln,

a) Glutamine dissociates from the sensor domain in the NtrB protein, leading to activation of a histidine kinase transmitter domain in NtrB

b) glutamine binds to a sensor domain of NtrB, causing a conformational change in the protein that inhibits its histidine kinase activity, the regulatory domain of NtrC blocks its DNA-binding domain from binding the glnA enhancers.

c) Activated transmitter domain of NtrB that transfers the γ-phosphate of ATP to a histidine residue (H), this phosphohistidine then transfers the phosphate to an aspartic acid residue (D) in the NtrC protein

d) This causes a conformational change in NtrC that unmasks the NtrC DNA-binding domain so that it can bind to the glnA enhancers

Which of the following combination is correct?

#Question id: 24164

#General Aptitude