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TLS Online TPP Program

#Id: 1353

GRB2 SH2 domain binds to a specific phosphotyrosine residue in the cytosolic domain of an activated RTK.

 

#Unit 4. Cell Communication and Cell Signaling #RTK #Part B Pointers
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TLS Online TPP Program

#Id: 1689

#Unit 4. Cell Communication and Cell Signaling

Light-chain recombination occurs at the small pre-B-cell stage of B-cell development.
TLS Online TPP Program

#Id: 1690

#Unit 4. Cell Communication and Cell Signaling

Site of DNA cleavage- Recombination Signal Sequence (RSS) 
TLS Online TPP Program

#Id: 1691

#Unit 4. Cell Communication and Cell Signaling
TLS Online TPP Program

#Id: 1692

#Unit 4. Cell Communication and Cell Signaling

Recognition of Recombination Signal Sequence (RSS) by the RAG1/RAG2 enzyme complex.
TLS Online TPP Program

#Id: 1693

#Unit 4. Cell Communication and Cell Signaling

RAG1 is expressed at all phases of the cell cycle, RAG2 is stable only in G0- or G1-phase cells.
TLS Online TPP Program

#Id: 1694

#Unit 4. Cell Communication and Cell Signaling

Threonine residue T490 on RAG2 is phosphorylated during the S, G2, and M phases of the cell cycle, and this phosphorylation triggers the destruction of RAG2.